Rctd-031 _verified_ Here

Interpretation of Hypothetical Results

| Cohort | Indication | Sample Size | Primary Endpoint | |--------|------------|-------------|------------------| | A | IPF (moderate disease) | 45 pts | Change in % predicted Forced Vital Capacity (FVC) at 24 weeks | | B | hATTR (stage 1–2) | 38 pts | Reduction in serum TTR‑aggregate levels at 12 weeks | | C | Safety/Pharmacokinetics (healthy volunteers) | 24 pts | Incidence of treatment‑emergent adverse events (TEAEs) |

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| Condition | Pathophysiology | |-----------|-----------------| | Idiopathic Pulmonary Fibrosis (IPF) | Excessive myofibroblast activation → collagen deposition | | Hereditary Transthyretin Amyloidosis (hATTR) | Misfolded transthyretin aggregates trigger fibro‑inflammatory response | | Certain forms of systemic sclerosis | Persistent fibroblast activation drives skin and organ fibrosis |

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After the first successful connection, the device will automatically reconnect to the same network on power‑up.

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